deltatrials
Active Not Recruiting OBSERVATIONAL NCT04537871

Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study

Cardiovascular Reserve Evaluation in Survivors of Transplantation (CREST)

Sponsor: City of Hope Medical Center

Conditions Acute Lymphoblastic Leukemia Acute Myeloid Leukemia Hematopoietic and Lymphoid Cell Neoplasm Hodgkin Lymphoma Myelodysplastic Syndrome Non-Hodgkin Lymphoma Plasma Cell Myeloma
Interventions Bioelectric Impedance Analysis Biospecimen Collection Cardiopulmonary Exercise Testing Echocardiography Physical Performance Testing Pulmonary Function Test Questionnaire Administration Ultrasound
Updated 13 times since 2020 Last updated: Sep 19, 2025 Started: Nov 18, 2020 Primary completion: Jun 30, 2026 Completion: Jun 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04537871, this observational or N/A phase trial focuses on Acute Lymphoblastic Leukemia and Acute Myeloid Leukemia and remains ongoing. Sponsored by City of Hope Medical Center, it has been updated 13 times since 2020, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Dec 2021 · 9 months · monthly snapshot~Dec 2021 – ~Apr 2022 · 4 months · monthly snapshot~Apr 2022 – ~Apr 2023 · 12 months · monthly snapshot~Apr 2023 – ~Nov 2023 · 7 months · monthly snapshot~Nov 2023 – ~Jun 2024 · 7 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Oct 2025 · 8 months · monthly snapshot~Oct 2025 – present · 9 months · monthly snapshot

Change History

13 versions recorded

  1. Oct 2025 — Present [monthly]

    Active Not Recruiting

  2. Feb 2025 — Oct 2025 [monthly]

    Active Not Recruiting

    Status: Recruiting → Active Not Recruiting

  3. Sep 2024 — Feb 2025 [monthly]

    Recruiting

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting

  5. Jun 2024 — Jul 2024 [monthly]

    Recruiting

▶ Show 8 earlier versions

  1. Nov 2023 — Jun 2024 [monthly]

    Recruiting

  2. Apr 2023 — Nov 2023 [monthly]

    Recruiting

  3. Apr 2022 — Apr 2023 [monthly]

    Recruiting

  4. Dec 2021 — Apr 2022 [monthly]

    Recruiting

  5. Mar 2021 — Dec 2021 [monthly]

    Recruiting

  6. Jan 2021 — Mar 2021 [monthly]

    Recruiting

  7. Nov 2020 — Jan 2021 [monthly]

    Recruiting

  8. Oct 2020 — Nov 2020 [monthly]

    Recruiting

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • City of Hope Medical Center
  • National Cancer Institute (NCI)
  • National Heart, Lung, and Blood Institute (NHLBI)
Data source: City of Hope Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations