deltatrials
Active Not Recruiting PHASE1 INTERVENTIONAL 5-arm NCT04544748

A Phase 1 Study of GNR-051 in Subjects With Advanced Malignancies

A Multicenter Open-Label Multi-Cohort Dose-Escalation Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of GNR-051 (GENERIUM JSC, Russia) in Subjects With Solid Advanced Malignancies

Sponsor: AO GENERIUM

Conditions Carcinoma, Non-Small-Cell Lung Carcinoma, Renal Cell Melanoma
Interventions GNR-051
Updated 8 times since 2020 Last updated: Mar 5, 2024 Started: Jul 22, 2020 Primary completion: Nov 7, 2022 Completion: Jan 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Carcinoma, Non-Small-Cell Lung and Carcinoma, Renal Cell and is currently ongoing. AO GENERIUM leads this study, which shows 8 recorded versions since 2020 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshotRecruiting~Oct 2021 – ~Mar 2023 · 17 months · monthly snapshotRecruiting~Mar 2023 – ~Apr 2024 · 13 months · monthly snapshotActive Not Recruiting~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotActive Not Recruiting~Sep 2025 – present · 10 months · monthly snapshotActive Not Recruiting

Change History

8 versions recorded

  1. Sep 2025 — Present [monthly]

    Active Not Recruiting PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Active Not Recruiting PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  4. Apr 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

  5. Mar 2023 — Apr 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

▶ Show 3 earlier versions

  1. Oct 2021 — Mar 2023 [monthly]

    Recruiting PHASE1

  2. Jan 2021 — Oct 2021 [monthly]

    Recruiting PHASE1

  3. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

    First recorded

Jul 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AO GENERIUM
Data source: AO GENERIUM

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations