deltatrials
Recruiting PHASE1/PHASE2 INTERVENTIONAL 6-arm NCT04601584

GNR-084 Safety and Pharmacological Characteristics in Refractory or Relapse B-cell Precursor ALL

Dose-escalation Sequention Cohort Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GNR-084 in Patients With Refractory or Relapse Acute Lymphoblastic B-cell Precursor Leukemia.

Sponsor: AO GENERIUM

Updated 9 times since 2020 Last updated: Mar 5, 2024 Started: Oct 15, 2020 Primary completion: Feb 28, 2025 Completion: Jun 30, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on ALL and B-precursor Acute Lymphoblastic Leukemia, this trial is actively recruiting participants. The trial is conducted by AO GENERIUM and has accumulated 9 data snapshots since 2020. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotRecruiting~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotRecruiting~Feb 2021 – ~Nov 2021 · 9 months · monthly snapshotRecruiting~Nov 2021 – ~Mar 2023 · 16 months · monthly snapshotRecruiting~Mar 2023 – ~Apr 2024 · 13 months · monthly snapshotRecruiting~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotRecruiting~Sep 2025 – present · 10 months · monthly snapshotRecruiting

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Recruiting PHASE1/PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Recruiting PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  4. Apr 2024 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

  5. Mar 2023 — Apr 2024 [monthly]

    Recruiting PHASE1_PHASE2

Show 4 earlier versions
  1. Nov 2021 — Mar 2023 [monthly]

    Recruiting PHASE1_PHASE2

  2. Feb 2021 — Nov 2021 [monthly]

    Recruiting PHASE1_PHASE2

  3. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE1_PHASE2

  4. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Oct 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AO GENERIUM
Data source: AO GENERIUM

For direct contact, visit the study record on ClinicalTrials.gov .