deltatrials
Completed PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT04545060

VIR-7831 for the Early Treatment of COVID-19 in Outpatients (COMET-ICE)

A Phase II/III Randomized, Multi-center, Double-blind, Placebo-controlled Study to Assess the Safety and Efficacy of Monoclonal Antibody VIR-7831 for the Early Treatment of Coronavirus Disease 2019 (COVID-19) in Non-hospitalized Patients

Sponsor: GlaxoSmithKline

Conditions Covid19
Updated 13 times since 2020 Last updated: Oct 12, 2022 Started: Aug 27, 2020 Primary completion: Apr 8, 2021 Completion: Sep 2, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2/PHASE3 trial investigates Covid19 and is currently completed. GlaxoSmithKline leads this study, which shows 13 recorded versions since 2020 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Apr 2021 · 59 days · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Dec 2022 · 14 months · monthly snapshot~Dec 2022 – ~Jul 2024 · 19 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2/PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2/PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2/PHASE3

    Phase: PHASE2_PHASE3PHASE2/PHASE3

  4. Dec 2022 — Jul 2024 [monthly]

    Completed PHASE2_PHASE3

  5. Oct 2021 — Dec 2022 [monthly]

    Completed PHASE2_PHASE3

    Status: Active Not RecruitingCompleted

Show 8 earlier versions
  1. Sep 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  2. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  3. Apr 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE2_PHASE3

    Status: RecruitingActive Not Recruiting

  4. Feb 2021 — Apr 2021 [monthly]

    Recruiting PHASE2_PHASE3

  5. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE2_PHASE3

  6. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE2_PHASE3

  7. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE2_PHASE3

  8. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE2_PHASE3

    First recorded

Aug 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • GlaxoSmithKline
  • Vir Biotechnology, Inc.
Data source: Vir Biotechnology, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .