deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT04554459

Ponatinib Plus Reduced-intensity Chemotherapy in the First-line Treatment of Adult Patients With Ph+ ALL (Pona-CELL)

Ponatinib Plus Reduced-intensity Chemotherapy in the First-line Treatment of Adult Patients With Ph-positive Acute Lymphoblastic Leukemia

Sponsor: CZECRIN - Czech Clinical Research Infrastructure Network

Updated 12 times since 2020 Last updated: Aug 13, 2024 Started: Feb 16, 2021 Primary completion: Sep 1, 2023 Completion: Jul 1, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

slower recruitment rate;

This PHASE2 trial investigates Acute Lymphoblastic Leukemia, Adult and Newly Diagnosed and is currently terminated or withdrawn. CZECRIN - Czech Clinical Research Infrastructure Network leads this study, which shows 12 recorded versions since 2021 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshotNot Yet Recruiting~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshotRecruiting~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshotRecruiting~Sep 2021 – ~May 2022 · 8 months · monthly snapshotRecruiting~May 2022 – ~Sep 2022 · 4 months · monthly snapshotRecruiting~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshotRecruiting~Dec 2022 – ~Feb 2024 · 14 months · monthly snapshotActive Not Recruiting~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshotSuspended~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotSuspended~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

    Status: SuspendedTerminated

  3. Jul 2024 — Sep 2024 [monthly]

    Suspended PHASE2

  4. Feb 2024 — Jul 2024 [monthly]

    Suspended PHASE2

    Status: Active Not RecruitingSuspended

  5. Dec 2022 — Feb 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

Show 7 earlier versions
  1. Sep 2022 — Dec 2022 [monthly]

    Recruiting PHASE2

  2. May 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  3. Sep 2021 — May 2022 [monthly]

    Recruiting PHASE2

  4. Apr 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  5. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  6. Jan 2021 — Mar 2021 [monthly]

    Not Yet Recruiting PHASE2

  7. Oct 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • CZECRIN - Czech Clinical Research Infrastructure Network
  • Institute of Hematology and Blood Transfusion, Czech Republic
Data source: Institute of Hematology and Blood Transfusion, Czech Republic

For direct contact, visit the study record on ClinicalTrials.gov .