deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT04592419

A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Patients With Macular Edema Due to Retinal Vein Occlusion (RVO) (BEACON)

A Prospective, Randomized, Double-masked, Active Comparator-controlled, Multi-center, Two-arm, Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Visual Impairment Due to Treatment-naïve Macular Edema Secondary to Retinal Vein Occlusion (RVO)

Sponsor: Kodiak Sciences Inc

Updated 10 times since 2020 Last updated: Jun 14, 2024 Started: Sep 25, 2020 Primary completion: Jun 10, 2022 Completion: Jan 19, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Macular Edema and Retinal Vein Occlusion, this trial is completed. The trial is conducted by Kodiak Sciences Inc and has accumulated 10 data snapshots since 2020. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Sep 2021 · 6 months · monthly snapshotRecruiting~Sep 2021 – ~Jul 2022 · 10 months · monthly snapshotRecruiting~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Mar 2023 · 6 months · monthly snapshotActive Not Recruiting~Mar 2023 – ~Jul 2024 · 16 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 11 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Mar 2023 — Jul 2024 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  5. Sep 2022 — Mar 2023 [monthly]

    Active Not Recruiting PHASE3

Show 5 earlier versions
  1. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  2. Sep 2021 — Jul 2022 [monthly]

    Recruiting PHASE3

  3. Mar 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  4. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE3

  5. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

    First recorded

Sep 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Kodiak Sciences Inc
Data source: Kodiak Sciences Inc

For direct contact, visit the study record on ClinicalTrials.gov .