deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT04601467

PASSIvation of Vulnerable Plaque With AZD5718 in AcuTe Coronary syndromE (PASSIVATE)

Sponsor: AstraZeneca

Interventions AZD5718 Placebo
Updated 7 times since 2020 Last updated: Apr 23, 2025 Started: Jul 12, 2021 Primary completion: May 27, 2024 Completion: Aug 14, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study was terminated early on 14th September 2023 by the main funding company because of financial futility. We were able to enroll 243 of the initial planned 360 participants and randomised 209 participants of the intial planned 286.

A PHASE2 clinical study on Acute Coronary Syndrome, this trial is terminated or withdrawn. The trial is conducted by AstraZeneca and has accumulated 7 data snapshots since 2021. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Jan 2023 · 24 months · monthly snapshotNot Yet Recruiting~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshot~Jan 2025 – ~May 2025 · 4 months · monthly snapshot~May 2025 – present · 15 months · monthly snapshotTerminated

Change History

7 versions recorded
  1. May 2025 — Present [monthly]

    Terminated PHASE2

    Status: UnknownTerminated

  2. Jan 2025 — May 2025 [monthly]

    Unknown PHASE2

    Status: RecruitingUnknown

  3. Sep 2024 — Jan 2025 [monthly]

    Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  5. Jan 2023 — Jul 2024 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

Show 2 earlier versions
  1. Jan 2021 — Jan 2023 [monthly]

    Not Yet Recruiting PHASE2

  2. Nov 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • National University Heart Centre, Singapore
  • University of Otago
Data source: National University Heart Centre, Singapore

For direct contact, visit the study record on ClinicalTrials.gov .