Completed PHASE2 INTERVENTIONAL 2-arm NCT04608396

Mechanistic Evaluation of Response in TRD (MERIT) (MERIT)

MERIT: A Randomized, Double-blind, Placebo-controlled Study of AXS-05 for Relapse Prevention in Treatment Resistant Depression

Sponsor: Axsome Therapeutics, Inc.

Conditions Major Depressive Disorder Treatment Resistant Depression

Interventions AXS-05 Placebo

Updated 7 times since 2020 Last updated: Jul 8, 2022 Started: Aug 13, 2020 Primary completion: Jul 30, 2021 Completion: Jul 30, 2021

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Major Depressive Disorder and Treatment Resistant Depression and is currently completed. Axsome Therapeutics, Inc. leads this study, which shows 7 recorded versions since 2020 — indicating limited longitudinal coverage. This study adds to the longitudinal dataset for psychiatric treatment development.

Status Flow

Change History

7 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Sep 2022 — Jul 2024 [monthly]

Completed PHASE2
Oct 2021 — Sep 2022 [monthly]

Completed PHASE2

Status: Recruiting → Completed
Apr 2021 — Oct 2021 [monthly]

Recruiting PHASE2

▶ Show 2 earlier versions

Jan 2021 — Apr 2021 [monthly]

Recruiting PHASE2
Nov 2020 — Jan 2021 [monthly]

Recruiting PHASE2

First recorded

Aug 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Axsome Therapeutics, Inc.

Data source: Axsome Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Berlin, United States , Boston, United States , Chicago, United States , Cincinnati, United States , Dallas, United States , Everett, United States , Hickory, United States , Houston, United States , Little Rock, United States , Media, United States and 10 more locations