deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT04631484

International Trial of Efficacy of Cytoflavin in Head Trauma (MITRA)

International, Multicenter, Randomized, Single Blind, Placebo-controlled Study of Efficacy and Safety of CITOFLAVIN® in the Acute Period of Head Injury in Adults

Sponsor: POLYSAN Scientific & Technological Pharmaceutical Company

Conditions Head Trauma,Closed
Interventions Cytoflavin ((Inosine + Nicotinamide + Riboflavin + Succinic Acid) Placebo
Updated 10 times since 2020 Last updated: Apr 15, 2025 Started: Nov 22, 2020 Primary completion: May 7, 2024 Completion: Sep 24, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Head Trauma,Closed and is currently completed. POLYSAN Scientific & Technological Pharmaceutical Company leads this study, which shows 10 recorded versions since 2020 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotActive Not Recruiting~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotActive Not Recruiting~Sep 2021 – ~Nov 2022 · 14 months · monthly snapshotRecruiting~Nov 2022 – ~Jan 2024 · 14 months · monthly snapshotRecruiting~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshotRecruiting~Oct 2024 – ~May 2025 · 7 months · monthly snapshotCompleted~May 2025 – ~Sep 2025 · 4 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

10 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. May 2025 — Sep 2025 [monthly]

    Completed PHASE3

  3. Oct 2024 — May 2025 [monthly]

    Completed PHASE3

    Status: Recruiting → Completed

  4. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE3

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

▶ Show 5 earlier versions

  1. Jan 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

  2. Nov 2022 — Jan 2024 [monthly]

    Recruiting PHASE3

  3. Sep 2021 — Nov 2022 [monthly]

    Recruiting PHASE3

    Status: Active Not Recruiting → Recruiting

  4. Jan 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE3

  5. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Nov 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • POLYSAN Scientific & Technological Pharmaceutical Company
Data source: POLYSAN Scientific & Technological Pharmaceutical Company

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations