deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT04649203

Cytoflavin in the Treatment of Patients With Diabetic Polyneuropathy (CYLINDER)

Multicenter, Double-blind, Placebo-controlled Randomized Clinical Trial of Efficacy and Safety of the Drug Cytoflavin®, Administered Intravenously Followed by Oral Intake, in Patients With Diabetic Polyneuropathy

Sponsor: POLYSAN Scientific & Technological Pharmaceutical Company

Conditions Diabetic Neuropathies
Interventions Cytoflavin (Inosine + Nicotinamide + Riboflavin + Succinic Acid) Placebo
Updated 8 times since 2021 Last updated: Jan 25, 2023 Started: Nov 25, 2020 Primary completion: Mar 29, 2021 Completion: Jun 6, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Diabetic Neuropathies, this trial is completed. The trial is conducted by POLYSAN Scientific & Technological Pharmaceutical Company and has accumulated 8 data snapshots since 2020. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotRecruiting~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshotCompleted~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshotCompleted~Mar 2022 – ~Feb 2023 · 11 months · monthly snapshotCompleted~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

8 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Feb 2023 — Jul 2024 [monthly]

    Completed PHASE3

  5. Mar 2022 — Feb 2023 [monthly]

    Completed PHASE3

▶ Show 3 earlier versions

  1. Feb 2022 — Mar 2022 [monthly]

    Completed PHASE3

  2. Sep 2021 — Feb 2022 [monthly]

    Completed PHASE3

    Status: Recruiting → Completed

  3. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

    First recorded

Nov 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • POLYSAN Scientific & Technological Pharmaceutical Company
Data source: POLYSAN Scientific & Technological Pharmaceutical Company

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations