deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT04644315

A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors (ALpha-T)

A Phase II, Open-Label, Single Arm Decentralized Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors

Sponsor: Hoffmann-La Roche

Conditions Brain Neoplasms Bronchial Neoplasms Carcinoma, Bronchogenic Central Nervous System Cholangiocarcinoma Colonic Diseases Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Head and Neck Neoplasms Intestinal Diseases Intestinal Neoplasms Lymphoma, Large-Cell, Anaplastic Melanoma Neoplasms Neoplasms by Site Neuroendocrine Tumors Ovarian Neoplasms Pancreatic Neoplasms Respiratory Tract Diseases Respiratory Tract Neoplasms Salivary Gland Neoplasms Sarcoma Thoracic Neoplasms Thyroid Cancer, Papillary Thyroid Neoplasms
Interventions Alectinib
Updated 23 times since 2020 Last updated: Jul 17, 2023 Started: May 24, 2021 Primary completion: May 16, 2022 Completion: May 16, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The data from this study is no longer needed.

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This PHASE2 trial investigates Brain Neoplasms and Bronchial Neoplasms and is currently terminated or withdrawn. Hoffmann-La Roche leads this study, which shows 23 recorded versions since 2021 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Sep 2023 · 12 months · monthly snapshot~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

23 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Sep 2023 — Jul 2024 [monthly]

    Terminated PHASE2

  5. Sep 2022 — Sep 2023 [monthly]

    Terminated PHASE2

▶ Show 18 earlier versions

  1. Jul 2022 — Sep 2022 [monthly]

    Terminated PHASE2

    Status: Recruiting → Terminated

  2. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE2

  3. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE2

  4. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE2

  5. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE2

  6. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE2

  7. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE2

  8. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE2

  9. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE2

  10. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE2

  11. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE2

  12. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  13. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE2

  14. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE2

  15. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

  16. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  17. Jan 2021 — Feb 2021 [monthly]

    Not Yet Recruiting PHASE2

  18. Dec 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Hoffmann-La Roche
Data source: Hoffmann-La Roche

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Austin, United States , Buffalo, United States , Culver City, United States , Dallas, United States , Fort Wayne, United States , Houston, United States , Indianapolis, United States , Jacksonville, United States , Los Angeles, United States , Miami, United States and 14 more locations