A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic Purpura
A Phase 3b, Prospective, Open-label, Multicenter, Single Treatment Arm, Continuation Study of the Safety and Efficacy of TAK-755 (rADAMTS13, Also Known as BAX 930/SHP655) in the Prophylactic and On-demand Treatment of Subjects With Severe Congenital Thrombotic Thrombocytopenic Purpura (cTTP; Upshaw-Schulman Syndrome, or Hereditary Thrombotic Thrombocytopenic Purpura)
Sponsor: Shire
This PHASE3 trial investigates Thrombotic Thrombocytopenic Purpura (TTP) and is currently actively recruiting participants. Shire leads this study, which shows 14 recorded versions since 2021 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.
Status Flow
Change History
14 versions recorded-
Sep 2025 — Present [monthly]
Recruiting PHASE3
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May 2025 — Sep 2025 [monthly]
Recruiting PHASE3
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Sep 2024 — May 2025 [monthly]
Recruiting PHASE3
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Jul 2024 — Sep 2024 [monthly]
Recruiting PHASE3
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May 2024 — Jul 2024 [monthly]
Recruiting PHASE3
▶ Show 9 earlier versions
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Dec 2023 — May 2024 [monthly]
Recruiting PHASE3
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Jun 2023 — Dec 2023 [monthly]
Recruiting PHASE3
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May 2023 — Jun 2023 [monthly]
Recruiting PHASE3
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Nov 2022 — May 2023 [monthly]
Recruiting PHASE3
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May 2022 — Nov 2022 [monthly]
Recruiting PHASE3
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Sep 2021 — May 2022 [monthly]
Recruiting PHASE3
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Jun 2021 — Sep 2021 [monthly]
Recruiting PHASE3
Status: Not Yet Recruiting → Recruiting
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Apr 2021 — Jun 2021 [monthly]
Not Yet Recruiting PHASE3
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Jan 2021 — Apr 2021 [monthly]
Not Yet Recruiting PHASE3
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- Shire
- Takeda
- Takeda Development Center Americas, Inc.
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
A Coruña, Spain , Atlanta, United States , Barakaldo, Spain , Beijing, China , Bergamo, Italy , Bern, Switzerland , Buffalo, United States , Bunkyo City, Japan , Dublin, United States , Durham, United States and 13 more locations