deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT04684446

Study in Adults of AZD1222 and rAd26-S Administered as Heterologous Prime-Boost Regimen for the Prevention of COVID-19

A Phase I/II Single-Blinded Randomized Safety and Immunogenicity Study in Adults of AZD1222 and rAd26-S Administered as Heterologous Prime Boost Regimen for the Prevention of COVID 19

Sponsor: AstraZeneca

Conditions COVID-19
Interventions AZD1222 rAd26-S
Updated 9 times since 2021 Last updated: Jun 2, 2022 Started: Sep 15, 2021 Primary completion: Nov 26, 2021 Completion: Mar 29, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates COVID-19 and is currently completed. AstraZeneca leads this study, which shows 9 recorded versions since 2021 — indicating limited longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotNot Yet Recruiting~Feb 2021 – ~Apr 2021 · 59 days · monthly snapshotNot Yet Recruiting~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshotNot Yet Recruiting~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshotNot Yet Recruiting~Oct 2021 – ~Jul 2022 · 9 months · monthly snapshotRecruiting~Jul 2022 – ~Jul 2024 · 24 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  4. Jul 2022 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

    Status: RecruitingCompleted

  5. Oct 2021 — Jul 2022 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

Show 4 earlier versions
  1. Sep 2021 — Oct 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  2. Apr 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  3. Feb 2021 — Apr 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  4. Jan 2021 — Feb 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • R-Pharm
  • Russian Direct Investment Fund
  • The Gamaleya National Center of Epidemiology & Microbiology
Data source: R-Pharm

For direct contact, visit the study record on ClinicalTrials.gov .