deltatrials
Completed PHASE2/PHASE3 INTERVENTIONAL 8-arm NCT04973449

Phase II/III Study of AZD2816, for the Prevention of COVID-19 in Adults (AZD2816)

A Phase II/III Partially Double-Blinded, Randomised, Multinational, Active-Controlled Study in Both Previously Vaccinated and Unvaccinated Adults to Determine the Safety and Immunogenicity of AZD2816, a Vaccine for the Prevention of COVID-19 Caused by Variant Strains of SARS-CoV-2

Sponsor: AstraZeneca

Interventions AZD1222 AZD2816
Updated 13 times since 2021 Last updated: May 1, 2024 Started: Jun 27, 2021 Primary completion: Feb 4, 2022 Completion: Aug 2, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2/PHASE3 clinical study on COVID-19 and SARS-CoV-2, this trial is completed. The trial is conducted by AstraZeneca and has accumulated 13 data snapshots since 2021. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~Jul 2022 · 3 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Sep 2025 · 11 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2/PHASE3

  2. Oct 2024 — Sep 2025 [monthly]

    Completed PHASE2/PHASE3

  3. Sep 2024 — Oct 2024 [monthly]

    Completed PHASE2/PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2/PHASE3

    Phase: PHASE2_PHASE3PHASE2/PHASE3

  5. Feb 2023 — Jul 2024 [monthly]

    Completed PHASE2_PHASE3

Show 8 earlier versions
  1. Sep 2022 — Feb 2023 [monthly]

    Completed PHASE2_PHASE3

    Status: Active Not RecruitingCompleted

  2. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  3. Apr 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  4. Feb 2022 — Apr 2022 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  5. Jan 2022 — Feb 2022 [monthly]

    Active Not Recruiting PHASE2_PHASE3

    Status: RecruitingActive Not Recruiting

  6. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE2_PHASE3

  7. Oct 2021 — Dec 2021 [monthly]

    Recruiting PHASE2_PHASE3

  8. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE2_PHASE3

    First recorded

Jun 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .