deltatrials
Completed PHASE3 INTERVENTIONAL 1-arm NCT04760769

Open-label Trial in Parkinson's Disease (PD) (TEMPO-4)

58-Week Open-label Trial of Tavapadon in Parkinson's Disease (TEMPO-4 Trial)

Sponsor: AbbVie

Interventions Tavapadon
Updated 21 times since 2021 Last updated: Dec 19, 2025 Started: Feb 24, 2021 Primary completion: Dec 1, 2025 Completion: Dec 1, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Parkinson Disease and is currently completed. AbbVie leads this study, which shows 21 recorded versions since 2021 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Mar 2021 – ~Jun 2021 · 3 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Sep 2022 · 10 months · monthly snapshot~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshot~Jan 2023 – ~Mar 2023 · 59 days · monthly snapshot~Mar 2023 – ~Jun 2023 · 3 months · monthly snapshot~Jun 2023 – ~Sep 2023 · 3 months · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Dec 2023 · 2 months · monthly snapshot~Dec 2023 – ~Feb 2024 · 2 months · monthly snapshot~Feb 2024 – ~May 2024 · 3 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Jan 2025 · 31 days · monthly snapshot~Jan 2025 – ~Apr 2025 · 3 months · monthly snapshot~Apr 2025 – ~Sep 2025 · 5 months · monthly snapshot~Sep 2025 – ~Jan 2026 · 4 months · monthly snapshot~Jan 2026 – present · 6 months · monthly snapshot

Change History

21 versions recorded
  1. Jan 2026 — Present [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  2. Sep 2025 — Jan 2026 [monthly]

    Active Not Recruiting PHASE3

  3. Apr 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Jan 2025 — Apr 2025 [monthly]

    Active Not Recruiting PHASE3

  5. Dec 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE3

    Status: Enrolling By InvitationActive Not Recruiting

Show 16 earlier versions
  1. Sep 2024 — Dec 2024 [monthly]

    Enrolling By Invitation PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Enrolling By Invitation PHASE3

  3. May 2024 — Jul 2024 [monthly]

    Enrolling By Invitation PHASE3

  4. Feb 2024 — May 2024 [monthly]

    Enrolling By Invitation PHASE3

  5. Dec 2023 — Feb 2024 [monthly]

    Enrolling By Invitation PHASE3

  6. Oct 2023 — Dec 2023 [monthly]

    Enrolling By Invitation PHASE3

  7. Sep 2023 — Oct 2023 [monthly]

    Enrolling By Invitation PHASE3

  8. Jun 2023 — Sep 2023 [monthly]

    Enrolling By Invitation PHASE3

  9. Mar 2023 — Jun 2023 [monthly]

    Enrolling By Invitation PHASE3

  10. Jan 2023 — Mar 2023 [monthly]

    Enrolling By Invitation PHASE3

  11. Sep 2022 — Jan 2023 [monthly]

    Enrolling By Invitation PHASE3

    Status: RecruitingEnrolling By Invitation

  12. Nov 2021 — Sep 2022 [monthly]

    Recruiting PHASE3

  13. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE3

  14. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  15. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  16. Mar 2021 — Jun 2021 [monthly]

    Recruiting PHASE3

    First recorded

Feb 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AbbVie
Data source: AbbVie

For direct contact, visit the study record on ClinicalTrials.gov .