deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT05581823

Study to Evaluate the Effects of Cytochrome P450 (CYP) 3A4 Inducer Carbamazepine on Tavapadon Pharmacokinetics in Healthy Adult Participants

A Phase 1, Open-label, Fixed-sequence, Crossover Trial to Evaluate the Effects of Cytochrome P450 (CYP) 3A4 Induction by Carbamazepine on the Steady-state Pharmacokinetics of Tavapadon in Healthy Adult Participants

Sponsor: Cerevel Therapeutics, LLC

Conditions Parkinson Disease
Interventions Carbamazepine Tavapadon
Updated 8 times since 2022 Last updated: Apr 19, 2023 Started: Oct 19, 2022 Primary completion: Jan 27, 2023 Completion: Feb 2, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05581823, this PHASE1 trial focuses on Parkinson Disease and remains completed. Sponsored by Cerevel Therapeutics, LLC, it has been updated 8 times since 2022, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshotRecruiting~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotRecruiting~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshotRecruiting~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshotActive Not Recruiting~Apr 2023 – ~May 2023 · 30 days · monthly snapshotActive Not Recruiting~May 2023 – ~Jul 2024 · 14 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

8 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. May 2023 — Jul 2024 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  4. Apr 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE1

  5. Feb 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

▶ Show 3 earlier versions

  1. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE1

  2. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE1

  3. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE1

    First recorded

Oct 2022

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cerevel Therapeutics, LLC
Data source: Cerevel Therapeutics, LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations