deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT04770272

Study to Compare a Mono Atezolizumab Window Followed by a Atezolizumab - CTX Therapy With Atezolizumab - CTX Therapy (neoMono)

An Adaptive Randomized Neoadjuvant Two Arm Trial in Triple-negative Breast Cancer Comparing a Mono Atezolizumab Window Followed by a Atezolizumab - CTX Therapy With Atezolizumab - CTX Therapy (neoMono)

Sponsor: Palleos Healthcare GmbH

Updated 10 times since 2021 Last updated: Dec 18, 2025 Started: Mar 1, 2021 Primary completion: Jul 6, 2023 Completion: Oct 2, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The trial stopped recruitment prematurely after a first planned interim analysis of the first 100 pCR results (given that a probability of less than 2.5% of meeting the primary endpoint was estimated).

Listed as NCT04770272, this PHASE2 trial focuses on Triple-negative Breast Cancer and remains terminated or withdrawn. Sponsored by Palleos Healthcare GmbH, it has been updated 10 times since 2021, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshotNot Yet Recruiting~Apr 2021 – ~Feb 2022 · 10 months · monthly snapshotRecruiting~Feb 2022 – ~Dec 2022 · 10 months · monthly snapshotRecruiting~Dec 2022 – ~Dec 2023 · 12 months · monthly snapshotActive Not Recruiting~Dec 2023 – ~Feb 2024 · 2 months · monthly snapshotActive Not Recruiting~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshotActive Not Recruiting~Dec 2024 – ~Feb 2026 · 14 months · monthly snapshotCompleted~Feb 2026 – present · 4 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Feb 2026 — Present [monthly]

    Terminated PHASE2

    Status: CompletedTerminated

  2. Dec 2024 — Feb 2026 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  3. Sep 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Feb 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

Show 5 earlier versions
  1. Dec 2023 — Feb 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Dec 2022 — Dec 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Feb 2022 — Dec 2022 [monthly]

    Recruiting PHASE2

  4. Apr 2021 — Feb 2022 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  5. Mar 2021 — Apr 2021 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Palleos Healthcare GmbH
  • Phaon Scientific GmbH
  • Roche Pharma AG
  • University Hospital Erlangen
  • University Hospital, Essen
Data source: Palleos Healthcare GmbH

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations