deltatrials
Completed PHASE1 INTERVENTIONAL 10-arm NCT04785144

Safety and Immunogenicity Study of a SARS-CoV-2 (COVID-19) Variant Vaccine (mRNA-1273.351) in Naïve and Previously Vaccinated Adults

Phase 1, Open-Label, Randomized Study of the Safety and Immunogenicity of a SARS-CoV-2 Variant Vaccine (mRNA-1273.351) in Naïve and Previously Vaccinated Adults

Sponsor: ModernaTX, Inc.

Updated 16 times since 2021 Last updated: Mar 14, 2024 Started: Mar 31, 2021 Primary completion: Jul 5, 2022 Completion: Jul 5, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates COVID-19 and COVID-19 Immunisation and is currently completed. ModernaTX, Inc. leads this study, which shows 16 recorded versions since 2021 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Jan 2022 · 4 months · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Jun 2022 · 3 months · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshot~Jan 2023 – ~Jul 2023 · 6 months · monthly snapshot~Jul 2023 – ~Oct 2023 · 3 months · monthly snapshot~Oct 2023 – ~Apr 2024 · 6 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

16 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Apr 2024 — Jul 2024 [monthly]

    Completed PHASE1

  4. Oct 2023 — Apr 2024 [monthly]

    Completed PHASE1

  5. Jul 2023 — Oct 2023 [monthly]

    Completed PHASE1

Show 11 earlier versions
  1. Jan 2023 — Jul 2023 [monthly]

    Completed PHASE1

  2. Sep 2022 — Jan 2023 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  3. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE1

  4. Jun 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE1

  5. Mar 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE1

  6. Feb 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE1

  7. Jan 2022 — Feb 2022 [monthly]

    Active Not Recruiting PHASE1

  8. Sep 2021 — Jan 2022 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  9. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

  10. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  11. Apr 2021 — May 2021 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Mar 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • ModernaTX, Inc.
  • National Institute of Allergy and Infectious Diseases (NIAID)
Data source: National Institute of Allergy and Infectious Diseases (NIAID)

For direct contact, visit the study record on ClinicalTrials.gov .