deltatrials
Completed PHASE4 INTERVENTIONAL 3-arm NCT04792567

Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC) (AMA-VACC)

An Open-label Multicenter Study to Assess Response to SARS-CoV-2 modRNA Vaccines in Participants With Secondary Progressive Multiple Sclerosis Treated With Mayzent (Siponimod)

Sponsor: Novartis Pharmaceuticals

Updated 12 times since 2021 Last updated: Jun 17, 2024 Started: Apr 19, 2021 Primary completion: Sep 6, 2021 Completion: Aug 15, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE4 clinical study on Secondary Progressive Multiple Sclerosis, this trial is completed. The trial is conducted by Novartis Pharmaceuticals and has accumulated 12 data snapshots since 2021. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Apr 2021 – ~May 2021 · 30 days · monthly snapshotNot Yet Recruiting~May 2021 – ~Jun 2021 · 31 days · monthly snapshotNot Yet Recruiting~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshotRecruiting~Sep 2021 – ~Jan 2022 · 4 months · monthly snapshotRecruiting~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshotActive Not Recruiting~Feb 2022 – ~Sep 2022 · 7 months · monthly snapshotActive Not Recruiting~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshotCompleted~Jan 2023 – ~Jun 2024 · 17 months · monthly snapshotCompleted~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE4

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

  4. Jun 2024 — Jul 2024 [monthly]

    Completed PHASE4

  5. Jan 2023 — Jun 2024 [monthly]

    Completed PHASE4

Show 7 earlier versions
  1. Sep 2022 — Jan 2023 [monthly]

    Completed PHASE4

    Status: Active Not RecruitingCompleted

  2. Feb 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE4

  3. Jan 2022 — Feb 2022 [monthly]

    Active Not Recruiting PHASE4

    Status: RecruitingActive Not Recruiting

  4. Sep 2021 — Jan 2022 [monthly]

    Recruiting PHASE4

  5. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE4

    Status: Not Yet RecruitingRecruiting

  6. May 2021 — Jun 2021 [monthly]

    Not Yet Recruiting PHASE4

  7. Apr 2021 — May 2021 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis Pharmaceuticals
Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .