deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT04786964

Study of Pemetrexed+Platinum Chemotherapy With or Without Cosibelimab in First Line Metastatic Non-squamous NSCLC (CONTERNO)

A Randomized, Open-Label, Phase 3 Study of Cosibelimab (CK-301) in Combination With Platinum+Pemetrexed Chemotherapy in Subjects With First-Line Metastatic Non-squamous Non-Small Cell Lung Cancer

Sponsor: Checkpoint Therapeutics, Inc.

Updated 10 times since 2021 Last updated: Mar 17, 2025 Started: Dec 8, 2021 Primary completion: Dec 30, 2023 Completion: Dec 30, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Regional political conflict

Listed as NCT04786964, this PHASE3 trial focuses on Metastatic Non-squamous Non Small Cell Lung Cancer and remains terminated or withdrawn. Sponsored by Checkpoint Therapeutics, Inc., it has been updated 10 times since 2021, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~Sep 2022 · 5 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~May 2025 · 8 months · monthly snapshotTerminated~May 2025 – ~Sep 2025 · 4 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. May 2025 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Sep 2024 — May 2025 [monthly]

    Terminated PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  5. Feb 2023 — Jul 2024 [monthly]

    Terminated PHASE3

    Status: Active Not RecruitingTerminated

Show 5 earlier versions
  1. Sep 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  2. Apr 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

  3. Feb 2022 — Apr 2022 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  4. Sep 2021 — Feb 2022 [monthly]

    Not Yet Recruiting PHASE3

  5. Apr 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Checkpoint Therapeutics, Inc.
Data source: Checkpoint Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .