deltatrials
Active Not Recruiting PHASE4 INTERVENTIONAL 2-arm NCT04790370

Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism (HI-PEITHO)

A Randomized Trial of Ultrasound-facilitated, Catheter-directed, Thrombolysis Versus Anticoagulation for Acute Intermediate-high Risk Pulmonary Embolism: The Higher-risk Pulmonary Embolism Thrombolysis Study

Sponsor: Boston Scientific Corporation

Updated 50 times since 2021 Last updated: Feb 21, 2026 Started: Aug 2, 2021 Primary completion: Jul 31, 2025 Completion: Aug 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Pulmonary Embolism and is currently ongoing. Boston Scientific Corporation leads this study, which shows 50 recorded versions since 2021 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Jan 2025 · 31 days · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Feb 2026 · 3 months · monthly snapshot~Feb 2026 – present · 7 months · monthly snapshot

Change History

50 versions recorded
  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE4

  2. Nov 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE4

  3. Oct 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE4

  4. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting PHASE4

    Status: RecruitingActive Not Recruiting

  5. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE4

Show 45 earlier versions
  1. Jul 2025 — Aug 2025 [monthly]

    Recruiting PHASE4

  2. Jun 2025 — Jul 2025 [monthly]

    Recruiting PHASE4

  3. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE4

  4. Apr 2025 — May 2025 [monthly]

    Recruiting PHASE4

  5. Mar 2025 — Apr 2025 [monthly]

    Recruiting PHASE4

  6. Feb 2025 — Mar 2025 [monthly]

    Recruiting PHASE4

  7. Jan 2025 — Feb 2025 [monthly]

    Recruiting PHASE4

  8. Dec 2024 — Jan 2025 [monthly]

    Recruiting PHASE4

  9. Nov 2024 — Dec 2024 [monthly]

    Recruiting PHASE4

  10. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE4

  11. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE4

  12. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE4

  13. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE4

  14. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE4

  15. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE4

  16. Apr 2024 — May 2024 [monthly]

    Recruiting PHASE4

  17. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE4

  18. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE4

  19. Jan 2024 — Feb 2024 [monthly]

    Recruiting PHASE4

  20. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE4

  21. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE4

  22. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE4

  23. Sep 2023 — Oct 2023 [monthly]

    Recruiting PHASE4

  24. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE4

  25. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE4

  26. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE4

  27. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE4

  28. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE4

  29. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE4

  30. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE4

  31. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE4

  32. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE4

  33. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE4

  34. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE4

  35. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE4

  36. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE4

  37. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE4

  38. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE4

  39. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE4

  40. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE4

  41. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE4

  42. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE4

  43. Oct 2021 — Dec 2021 [monthly]

    Recruiting PHASE4

  44. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE4

    Status: Not Yet RecruitingRecruiting

  45. Apr 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Boston Scientific Corporation
  • National PERT Consortium, Inc.
  • University Medical Center Mainz
Data source: Boston Scientific Corporation

For direct contact, visit the study record on ClinicalTrials.gov .