deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 1-arm NCT04803877

SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma

SARC038: A Phase 2 Study of Regorafenib in Combination With Nivolumab in Patients With Refractory or Recurrent Osteosarcoma

Sponsor: Sarcoma Alliance for Research through Collaboration

Updated 17 times since 2021 Last updated: Oct 29, 2025 Started: Jun 4, 2021 Primary completion: Nov 30, 2025 Completion: Jun 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Osteosarcoma and Osteosarcoma Metastatic, this trial is ongoing. The trial is conducted by Sarcoma Alliance for Research through Collaboration and has accumulated 17 data snapshots since 2021. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshot~Dec 2021 – ~Feb 2022 · 2 months · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~Jun 2022 · 2 months · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshot~Apr 2023 – ~Oct 2023 · 6 months · monthly snapshot~Oct 2023 – ~Jul 2024 · 9 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~May 2025 · 8 months · monthly snapshot~May 2025 – ~Nov 2025 · 6 months · monthly snapshot~Nov 2025 – present · 8 months · monthly snapshot

Change History

17 versions recorded
  1. Nov 2025 — Present [monthly]

    Active Not Recruiting PHASE2

  2. May 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Sep 2024 — May 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Oct 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

Show 12 earlier versions
  1. Apr 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Feb 2023 — Apr 2023 [monthly]

    Recruiting PHASE2

  3. Sep 2022 — Feb 2023 [monthly]

    Recruiting PHASE2

  4. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  5. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE2

  6. Apr 2022 — Jun 2022 [monthly]

    Recruiting PHASE2

  7. Feb 2022 — Apr 2022 [monthly]

    Recruiting PHASE2

  8. Dec 2021 — Feb 2022 [monthly]

    Recruiting PHASE2

  9. Oct 2021 — Dec 2021 [monthly]

    Recruiting PHASE2

  10. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  11. Jun 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE2

  12. Apr 2021 — Jun 2021 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Sarcoma Alliance for Research through Collaboration
Data source: Sarcoma Alliance for Research through Collaboration

For direct contact, visit the study record on ClinicalTrials.gov .