deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT04887259

Trial of LAVA-051 in Patients with Relapsed/refractory CLL, MM, or AML

A Phase 1 Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Antitumor Activity of LAVA-051 in Patients with Relapsed or Refractory CLL, MM, or AML

Sponsor: Lava Therapeutics

Updated 12 times since 2021 Last updated: Jan 23, 2025 Started: Jul 12, 2021 Primary completion: Sep 6, 2023 Completion: Sep 6, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The decision to discontinue LAVA-051clinical trial follows a recent review of the competitive landscape that has continued to evolve (Business decision). The decision is not due to safety concerns.

Other terminated trials from Lava Therapeutics

More terminations from Lava Therapeutics

A PHASE1 clinical study on Acute Myeloid Leukemia and Chronic Lymphocytic Leukemia, this trial is terminated or withdrawn. The trial is conducted by Lava Therapeutics and has accumulated 12 data snapshots since 2021. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshotRecruiting~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshotRecruiting~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshotRecruiting~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshotRecruiting~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshotRecruiting~Apr 2023 – ~May 2023 · 30 days · monthly snapshotRecruiting~May 2023 – ~Jun 2023 · 31 days · monthly snapshotRecruiting~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshotRecruiting~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshotActive Not Recruiting~Feb 2025 – present · 19 months · monthly snapshotTerminated

Change History

12 versions recorded
  1. Feb 2025 — Present [monthly]

    Terminated PHASE1

    Status: Active Not RecruitingTerminated · Phase: PHASE1/PHASE2PHASE1

  2. Sep 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  4. Jul 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  5. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE1_PHASE2

Show 7 earlier versions
  1. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE1_PHASE2

  2. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE1_PHASE2

  3. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE1_PHASE2

  4. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE1_PHASE2

  5. Sep 2022 — Feb 2023 [monthly]

    Recruiting PHASE1_PHASE2

  6. Sep 2021 — Sep 2022 [monthly]

    Recruiting PHASE1_PHASE2

  7. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Lava Therapeutics
Data source: Lava Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .