deltatrials
Enrolling By Invitation PHASE3 INTERVENTIONAL 1-arm NCT04905693

Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease (TETON-OLE)

An Open-label Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease (TETON-OLE)

Sponsor: United Therapeutics

Conditions Idiopathic Pulmonary Fibrosis Interstitial Lung Disease Progressive Pulmonary Fibrosis
Interventions Inhaled Treprostinil Treprostinil Ultrasonic Nebulizer
Updated 39 times since 2021 Last updated: Feb 27, 2026 Started: Sep 6, 2022 Primary completion: Jun 30, 2026 Completion: Jun 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease and is currently ongoing. United Therapeutics leads this study, which shows 39 recorded versions since 2022 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jun 2021 – ~Mar 2022 · 9 months · monthly snapshot~Mar 2022 – ~Jul 2022 · 4 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Apr 2025 · 4 months · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshot~Mar 2026 – present · 5 months · monthly snapshot

Change History

39 versions recorded

  1. Mar 2026 — Present [monthly]

    Enrolling By Invitation PHASE3

  2. Feb 2026 — Mar 2026 [monthly]

    Enrolling By Invitation PHASE3

  3. Jan 2026 — Feb 2026 [monthly]

    Enrolling By Invitation PHASE3

  4. Dec 2025 — Jan 2026 [monthly]

    Enrolling By Invitation PHASE3

  5. Nov 2025 — Dec 2025 [monthly]

    Enrolling By Invitation PHASE3

▶ Show 34 earlier versions

  1. Oct 2025 — Nov 2025 [monthly]

    Enrolling By Invitation PHASE3

  2. Sep 2025 — Oct 2025 [monthly]

    Enrolling By Invitation PHASE3

  3. Aug 2025 — Sep 2025 [monthly]

    Enrolling By Invitation PHASE3

  4. Jul 2025 — Aug 2025 [monthly]

    Enrolling By Invitation PHASE3

  5. Jun 2025 — Jul 2025 [monthly]

    Enrolling By Invitation PHASE3

  6. May 2025 — Jun 2025 [monthly]

    Enrolling By Invitation PHASE3

  7. Apr 2025 — May 2025 [monthly]

    Enrolling By Invitation PHASE3

  8. Dec 2024 — Apr 2025 [monthly]

    Enrolling By Invitation PHASE3

  9. Nov 2024 — Dec 2024 [monthly]

    Enrolling By Invitation PHASE3

  10. Oct 2024 — Nov 2024 [monthly]

    Enrolling By Invitation PHASE3

  11. Sep 2024 — Oct 2024 [monthly]

    Enrolling By Invitation PHASE3

  12. Jul 2024 — Sep 2024 [monthly]

    Enrolling By Invitation PHASE3

  13. Jun 2024 — Jul 2024 [monthly]

    Enrolling By Invitation PHASE3

  14. May 2024 — Jun 2024 [monthly]

    Enrolling By Invitation PHASE3

  15. Apr 2024 — May 2024 [monthly]

    Enrolling By Invitation PHASE3

  16. Mar 2024 — Apr 2024 [monthly]

    Enrolling By Invitation PHASE3

  17. Feb 2024 — Mar 2024 [monthly]

    Enrolling By Invitation PHASE3

  18. Jan 2024 — Feb 2024 [monthly]

    Enrolling By Invitation PHASE3

  19. Dec 2023 — Jan 2024 [monthly]

    Enrolling By Invitation PHASE3

  20. Nov 2023 — Dec 2023 [monthly]

    Enrolling By Invitation PHASE3

  21. Oct 2023 — Nov 2023 [monthly]

    Enrolling By Invitation PHASE3

  22. Sep 2023 — Oct 2023 [monthly]

    Enrolling By Invitation PHASE3

  23. Aug 2023 — Sep 2023 [monthly]

    Enrolling By Invitation PHASE3

  24. Jul 2023 — Aug 2023 [monthly]

    Enrolling By Invitation PHASE3

  25. Jun 2023 — Jul 2023 [monthly]

    Enrolling By Invitation PHASE3

  26. May 2023 — Jun 2023 [monthly]

    Enrolling By Invitation PHASE3

  27. Apr 2023 — May 2023 [monthly]

    Enrolling By Invitation PHASE3

  28. Mar 2023 — Apr 2023 [monthly]

    Enrolling By Invitation PHASE3

  29. Feb 2023 — Mar 2023 [monthly]

    Enrolling By Invitation PHASE3

  30. Jan 2023 — Feb 2023 [monthly]

    Enrolling By Invitation PHASE3

  31. Sep 2022 — Jan 2023 [monthly]

    Enrolling By Invitation PHASE3

  32. Jul 2022 — Sep 2022 [monthly]

    Enrolling By Invitation PHASE3

    Status: Not Yet Recruiting → Enrolling By Invitation

  33. Mar 2022 — Jul 2022 [monthly]

    Not Yet Recruiting PHASE3

  34. Jun 2021 — Mar 2022 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • United Therapeutics
Data source: United Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aalst, Belgium , Aarhus N, Denmark , Ajax, Canada , Albuquerque, United States , Amiens, France , Ancona, Italy , Anderlecht, Belgium , Ann Arbor, United States , Antwerp, Belgium , Ashkelon, Israel and 154 more locations