deltatrials
Completed PHASE1 INTERVENTIONAL 6-arm NCT04992520

Controlled Human Infection Model Challenge/Rechallenge

Controlled Human Infection Model Challenge/Rechallenge: Shigella Flexneri 2a and S. Sonnei Cross-protective Antigens Discovery in Healthy Adults in the United States

Sponsor: Johns Hopkins University Center for Immunization Research (CIR)

Conditions Shigellosis
Updated 9 times since 2021 Last updated: Dec 20, 2024 Started: Apr 26, 2022 Primary completion: Aug 29, 2023 Completion: Aug 29, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Shigellosis, this trial is completed. The trial is conducted by Johns Hopkins University Center for Immunization Research (CIR) and has accumulated 9 data snapshots since 2022. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshotNot Yet Recruiting~Oct 2021 – ~Jan 2022 · 3 months · monthly snapshotNot Yet Recruiting~Jan 2022 – ~May 2022 · 4 months · monthly snapshotRecruiting~May 2022 – ~Apr 2023 · 11 months · monthly snapshotRecruiting~Apr 2023 – ~Dec 2023 · 8 months · monthly snapshotActive Not Recruiting~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshotCompleted~Feb 2025 – present · 17 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Feb 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Feb 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Dec 2023 — Jul 2024 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  5. Apr 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

Show 4 earlier versions
  1. May 2022 — Apr 2023 [monthly]

    Recruiting PHASE1

  2. Jan 2022 — May 2022 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  3. Oct 2021 — Jan 2022 [monthly]

    Not Yet Recruiting PHASE1

  4. Sep 2021 — Oct 2021 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Johns Hopkins University Center for Immunization Research (CIR)
  • PATH
  • United States Department of Defense
Data source: PATH

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations