deltatrials
Recruiting PHASE1 INTERVENTIONAL 6-arm NCT05959616

Shigella Sonnei 53G Human Infection Study in Kenyan Adults

Safety and Feasibility of a Shigella Sonnei 53G Controlled Human Infection Model in Kenyan Adults: a Dose Finding and Dose Verification Study

Sponsor: Johns Hopkins University

Conditions Shigellosis
Updated 6 times since 2023 Last updated: Mar 10, 2025 Started: Jan 21, 2025 Primary completion: Apr 30, 2026 Completion: Aug 30, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05959616, this PHASE1 trial focuses on Shigellosis and remains actively recruiting participants. Sponsored by Johns Hopkins University, it has been updated 6 times since 2025, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Aug 2023 – ~Dec 2023 · 4 months · monthly snapshotNot Yet Recruiting~Dec 2023 – ~Jun 2024 · 6 months · monthly snapshotNot Yet Recruiting~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshotNot Yet Recruiting~Apr 2025 – present · 15 months · monthly snapshotRecruiting

Change History

6 versions recorded
  1. Apr 2025 — Present [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  2. Sep 2024 — Apr 2025 [monthly]

    Not Yet Recruiting PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Not Yet Recruiting PHASE1

  4. Jun 2024 — Jul 2024 [monthly]

    Not Yet Recruiting PHASE1

  5. Dec 2023 — Jun 2024 [monthly]

    Not Yet Recruiting PHASE1

Show 1 earlier version
  1. Aug 2023 — Dec 2023 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Johns Hopkins University
  • KEMRI United States Army Medical Research Directorate-Kenya
  • KEMRI-Wellcome Trust Collaborative Research Program
  • Naval Medical Research Center
  • PATH
  • University of Oxford
  • Walter Reed Army Institute of Research (WRAIR)
Data source: University of Oxford

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations