deltatrials
Completed PHASE4 INTERVENTIONAL 3-arm NCT05018091

Dexamethasone in Total Knee Arthroplasty

Dexamethasone in Total Knee Arthroplasty: What Dose Should we be Giving Patients Intraoperatively

Sponsor: Rush University Medical Center

Conditions Total Knee Arthroplasty
Interventions Dexamethasone 16mg Dexamethasone 4mg Dexamethasone 8 Mg/mL Injectable Suspension
Updated 18 times since 2021 Last updated: Jul 31, 2025 Started: Oct 28, 2021 Primary completion: Jan 1, 2025 Completion: May 30, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Total Knee Arthroplasty and is currently completed. Rush University Medical Center leads this study, which shows 18 recorded versions since 2021 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Mar 2022 · 4 months · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~Sep 2022 · 5 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Feb 2023 · 2 months · monthly snapshot~Feb 2023 – ~May 2023 · 3 months · monthly snapshot~May 2023 – ~Jan 2024 · 8 months · monthly snapshot~Jan 2024 – ~Apr 2024 · 3 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Dec 2024 · 2 months · monthly snapshot~Dec 2024 – ~Mar 2025 · 3 months · monthly snapshot~Mar 2025 – ~May 2025 · 2 months · monthly snapshot~May 2025 – ~Sep 2025 · 4 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

18 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE4

    Status: Active Not Recruiting → Completed

  2. May 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE4

  3. Mar 2025 — May 2025 [monthly]

    Active Not Recruiting PHASE4

  4. Dec 2024 — Mar 2025 [monthly]

    Active Not Recruiting PHASE4

  5. Oct 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE4

▶ Show 13 earlier versions

  1. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE4

  2. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE4

    Status: Recruiting → Active Not Recruiting

  3. Apr 2024 — Jul 2024 [monthly]

    Recruiting PHASE4

  4. Jan 2024 — Apr 2024 [monthly]

    Recruiting PHASE4

  5. May 2023 — Jan 2024 [monthly]

    Recruiting PHASE4

  6. Feb 2023 — May 2023 [monthly]

    Recruiting PHASE4

  7. Dec 2022 — Feb 2023 [monthly]

    Recruiting PHASE4

  8. Sep 2022 — Dec 2022 [monthly]

    Recruiting PHASE4

  9. Apr 2022 — Sep 2022 [monthly]

    Recruiting PHASE4

  10. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE4

  11. Nov 2021 — Mar 2022 [monthly]

    Recruiting PHASE4

    Status: Not Yet Recruiting → Recruiting

  12. Oct 2021 — Nov 2021 [monthly]

    Not Yet Recruiting PHASE4

  13. Sep 2021 — Oct 2021 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Rush University Medical Center
Data source: Rush University Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations