deltatrials
Terminated PHASE3 INTERVENTIONAL 1-arm NCT05074420

A Study of Baricitinib (LY3009104) in Children With COVID-19 (COV-BARRIER)

A Multicenter, Open-Label, Pharmacokinetic and Safety Study of Baricitinib in Pediatric Patients From 1 Year to Less Than 18 Years Old Hospitalized With COVID-19

Sponsor: Eli Lilly and Company

Conditions Corona Virus Infection Covid19
Interventions Baricitinib
Updated 33 times since 2021 Last updated: Dec 15, 2025 Started: Dec 21, 2021 Primary completion: Sep 5, 2024 Completion: Nov 4, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Study terminated due to an inability to enroll participants.

Other terminated trials from Eli Lilly and Company

See all terminations from Eli Lilly and Company

A PHASE3 clinical study on Corona Virus Infection and Covid19, this trial is terminated or withdrawn. The trial is conducted by Eli Lilly and Company and has accumulated 33 data snapshots since 2021. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Oct 2023 · 4 months · monthly snapshot~Oct 2023 – ~Feb 2024 · 4 months · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~May 2024 · 2 months · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~May 2025 · 3 months · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – present · 6 months · monthly snapshot

Change History

33 versions recorded

  1. Jan 2026 — Present [monthly]

    Terminated PHASE3

    Status: Recruiting → Terminated

  2. Dec 2025 — Jan 2026 [monthly]

    Recruiting PHASE3

  3. Nov 2025 — Dec 2025 [monthly]

    Recruiting PHASE3

  4. Oct 2025 — Nov 2025 [monthly]

    Recruiting PHASE3

  5. Sep 2025 — Oct 2025 [monthly]

    Recruiting PHASE3

▶ Show 28 earlier versions

  1. Jun 2025 — Sep 2025 [monthly]

    Recruiting PHASE3

  2. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE3

  3. Feb 2025 — May 2025 [monthly]

    Recruiting PHASE3

  4. Sep 2024 — Feb 2025 [monthly]

    Recruiting PHASE3

  5. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  6. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE3

  7. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

  8. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE3

  9. Mar 2024 — May 2024 [monthly]

    Recruiting PHASE3

  10. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE3

  11. Oct 2023 — Feb 2024 [monthly]

    Recruiting PHASE3

  12. Jun 2023 — Oct 2023 [monthly]

    Recruiting PHASE3

  13. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE3

  14. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE3

  15. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE3

  16. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE3

  17. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE3

  18. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE3

  19. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE3

  20. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE3

  21. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

  22. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE3

  23. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE3

  24. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE3

  25. Feb 2022 — Apr 2022 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  26. Jan 2022 — Feb 2022 [monthly]

    Not Yet Recruiting PHASE3

  27. Dec 2021 — Jan 2022 [monthly]

    Not Yet Recruiting PHASE3

  28. Nov 2021 — Dec 2021 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Eli Lilly and Company
Data source: Eli Lilly and Company

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Campinas, Brazil , Cleveland, United States , Detroit, United States , Jaú, Brazil , Madrid, Spain , Mexico City, Mexico , Orlando, United States , Pamplona, Spain , Porto Alegre, Brazil , Santo André, Brazil and 1 more location