Active Not Recruiting OBSERVATIONAL NCT05116293

Effect of Testosterone Treatment on Drug Metabolism and Transport

Effect of Gender-Affirming Testosterone Therapy on Drug Metabolism, Transport, and Gut Microbiota

Sponsor: University of Washington

Interventions Acetaminophen Oral Tablet Digoxin Oral Tablet Midazolam oral solution

Updated 8 times since 2021 Last updated: Jun 11, 2025 Started: May 1, 2021 Primary completion: Feb 15, 2024 Completion: Dec 31, 2025

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates Transgender Persons and is currently ongoing. University of Washington leads this study, which shows 8 recorded versions since 2021 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

8 versions recorded

Jul 2025 — Present [monthly]

Active Not Recruiting
Sep 2024 — Jul 2025 [monthly]

Active Not Recruiting
Jul 2024 — Sep 2024 [monthly]

Active Not Recruiting
Apr 2024 — Jul 2024 [monthly]

Active Not Recruiting
Sep 2023 — Apr 2024 [monthly]

Active Not Recruiting

Status: Recruiting → Active Not Recruiting

▶ Show 3 earlier versions

Jun 2023 — Sep 2023 [monthly]

Recruiting

Status: Active Not Recruiting → Recruiting
Jan 2023 — Jun 2023 [monthly]

Active Not Recruiting

Status: Recruiting → Active Not Recruiting
Dec 2021 — Jan 2023 [monthly]

Recruiting

First recorded

May 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

University of Washington

Data source: University of Washington

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Seattle, United States