Completed PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT05163808

A Randomized Study of BPN14770 in Male Adolescents (Aged 9 to < 18 Years) With Fragile X Syndrome

A Randomized, Double-blind, Placebo-controlled, Two-Part Study of BPN14770 in Male Adolescents (Aged 9 to < 18 Years) With Fragile X Syndrome

Sponsor: Tetra Discovery Partners

Conditions Fragile X Syndrome

Interventions Placebo zatolmilast

Updated 18 times since 2022 Last updated: Feb 2, 2026 Started: Mar 29, 2022 Primary completion: Sep 2, 2025 Completion: Sep 2, 2025

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2/PHASE3 clinical study on Fragile X Syndrome, this trial is completed. The trial is conducted by Tetra Discovery Partners and has accumulated 18 data snapshots since 2022. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

18 versions recorded

Feb 2026 — Present [monthly]

Completed PHASE2/PHASE3

Status: Active Not Recruiting → Completed
Sep 2025 — Feb 2026 [monthly]

Active Not Recruiting PHASE2/PHASE3
Jul 2025 — Sep 2025 [monthly]

Active Not Recruiting PHASE2/PHASE3
May 2025 — Jul 2025 [monthly]

Active Not Recruiting PHASE2/PHASE3

Status: Recruiting → Active Not Recruiting
Mar 2025 — May 2025 [monthly]

Recruiting PHASE2/PHASE3

▶ Show 13 earlier versions

Feb 2025 — Mar 2025 [monthly]

Recruiting PHASE2/PHASE3
Dec 2024 — Feb 2025 [monthly]

Recruiting PHASE2/PHASE3
Nov 2024 — Dec 2024 [monthly]

Recruiting PHASE2/PHASE3
Sep 2024 — Nov 2024 [monthly]

Recruiting PHASE2/PHASE3
Jul 2024 — Sep 2024 [monthly]

Recruiting PHASE2/PHASE3

Phase: PHASE2_PHASE3 → PHASE2/PHASE3
Mar 2024 — Jul 2024 [monthly]

Recruiting PHASE2_PHASE3
Feb 2024 — Mar 2024 [monthly]

Recruiting PHASE2_PHASE3
Jan 2024 — Feb 2024 [monthly]

Recruiting PHASE2_PHASE3
Nov 2023 — Jan 2024 [monthly]

Recruiting PHASE2_PHASE3
Jul 2023 — Nov 2023 [monthly]

Recruiting PHASE2_PHASE3
Mar 2023 — Jul 2023 [monthly]

Recruiting PHASE2_PHASE3
Jun 2022 — Mar 2023 [monthly]

Recruiting PHASE2_PHASE3

Status: Not Yet Recruiting → Recruiting
Jan 2022 — Jun 2022 [monthly]

Not Yet Recruiting PHASE2_PHASE3

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Tetra Discovery Partners

Data source: Tetra Discovery Partners

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Atlanta, United States , Aurora, United States , Baltimore, United States , Boston, United States , Chicago, United States , Cincinnati, United States , Greenville, United States , Irvine, United States , Kansas City, United States , Media, United States and 7 more locations