Recruiting PHASE3 INTERVENTIONAL 2-arm NCT05235165

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

A Phase 3 Randomized Controlled Trial Comparing Open vs Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Sponsor: Children's Oncology Group

Conditions Metastatic Malignant Neoplasm in the Lung Metastatic Osteosarcoma Osteosarcoma

Interventions Biospecimen Collection Computed Tomography Questionnaire Administration Thoracoscopy Thoracotomy

Updated 31 times since 2022 Last updated: Feb 24, 2026 Started: Apr 1, 2022 Primary completion: Mar 31, 2031 Completion: Mar 31, 2031

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Metastatic Malignant Neoplasm in the Lung and Metastatic Osteosarcoma and is currently actively recruiting participants. Children's Oncology Group leads this study, which shows 31 recorded versions since 2022 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

31 versions recorded

Feb 2026 — Present [monthly]

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▶ Show 26 earlier versions

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Status: Not Yet Recruiting → Recruiting
Mar 2022 — Apr 2022 [monthly]

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First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Children's Oncology Group
National Cancer Institute (NCI)

Data source: Children's Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Akron, United States , Albany, United States , Albuquerque, United States , Allentown, United States , Amarillo, United States , Anaheim, United States , Anchorage, United States , Ann Arbor, United States , Arroyo Grande, United States , Asheville, United States and 144 more locations