deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 2-arm NCT05257083

A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma (CARTITUDE-6)

A Phase 3 Randomized Study Comparing Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible

Sponsor: Janssen Research & Development, LLC

Updated 20 times since 2022 Last updated: Dec 17, 2025 Started: Oct 10, 2023 Primary completion: Jun 30, 2033 Completion: Aug 31, 2040
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Multiple Myeloma and is currently ongoing. Janssen Research & Development, LLC leads this study, which shows 20 recorded versions since 2023 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Mar 2022 – ~Sep 2022 · 6 months · monthly snapshot~Sep 2022 – ~Apr 2023 · 7 months · monthly snapshot~Apr 2023 – ~Sep 2023 · 5 months · monthly snapshot~Sep 2023 – ~Nov 2023 · 2 months · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Apr 2024 · 2 months · monthly snapshot~Apr 2024 – ~Jun 2024 · 2 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Feb 2025 · 2 months · monthly snapshot~Feb 2025 – ~Jun 2025 · 4 months · monthly snapshot~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Jan 2026 · 3 months · monthly snapshot~Jan 2026 – present · 8 months · monthly snapshot

Change History

20 versions recorded
  1. Jan 2026 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Oct 2025 — Jan 2026 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  3. Sep 2025 — Oct 2025 [monthly]

    Recruiting PHASE3

  4. Jun 2025 — Sep 2025 [monthly]

    Recruiting PHASE3

  5. Feb 2025 — Jun 2025 [monthly]

    Recruiting PHASE3

Show 15 earlier versions
  1. Dec 2024 — Feb 2025 [monthly]

    Recruiting PHASE3

  2. Nov 2024 — Dec 2024 [monthly]

    Recruiting PHASE3

  3. Sep 2024 — Nov 2024 [monthly]

    Recruiting PHASE3

  4. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  5. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE3

  6. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

  7. Apr 2024 — Jun 2024 [monthly]

    Recruiting PHASE3

  8. Feb 2024 — Apr 2024 [monthly]

    Recruiting PHASE3

  9. Jan 2024 — Feb 2024 [monthly]

    Recruiting PHASE3

  10. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE3

  11. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  12. Sep 2023 — Nov 2023 [monthly]

    Not Yet Recruiting PHASE3

  13. Apr 2023 — Sep 2023 [monthly]

    Not Yet Recruiting PHASE3

  14. Sep 2022 — Apr 2023 [monthly]

    Not Yet Recruiting PHASE3

  15. Mar 2022 — Sep 2022 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Janssen Research & Development, LLC
  • Stichting European Myeloma Network
Data source: European Myeloma Network B.V.

For direct contact, visit the study record on ClinicalTrials.gov .