deltatrials
Completed PHASE1 INTERVENTIONAL 4-arm NCT05287893

Pyronaridine in Healthy Adult Participants Infected With Blood Stage Malaria

A Phase 1b Study to Characterise the Pharmacokinetic/Pharmacodynamic Relationship of Pyronaridine in Healthy Adult Participants Experimentally Infected With Blood Stage Plasmodium Falciparum.

Sponsor: Children's Health Queensland Hospital and Health Service

Updated 8 times since 2022 Last updated: Apr 14, 2025 Started: Apr 4, 2022 Primary completion: Sep 26, 2022 Completion: Sep 26, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Malaria and Malaria Recrudescence and is currently completed. Children's Health Queensland Hospital and Health Service leads this study, which shows 8 recorded versions since 2022 — indicating limited longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Apr 2022 – ~May 2022 · 30 days · monthly snapshotNot Yet Recruiting~May 2022 – ~Dec 2022 · 7 months · monthly snapshotRecruiting~Dec 2022 – ~Feb 2023 · 2 months · monthly snapshotCompleted~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshotCompleted~Feb 2025 – ~May 2025 · 3 months · monthly snapshotCompleted~May 2025 – present · 14 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. May 2025 — Present [monthly]

    Completed PHASE1

  2. Feb 2025 — May 2025 [monthly]

    Completed PHASE1

  3. Sep 2024 — Feb 2025 [monthly]

    Completed PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  5. Feb 2023 — Jul 2024 [monthly]

    Completed PHASE1

Show 3 earlier versions
  1. Dec 2022 — Feb 2023 [monthly]

    Completed PHASE1

    Status: RecruitingCompleted

  2. May 2022 — Dec 2022 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  3. Apr 2022 — May 2022 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Children's Health Queensland Hospital and Health Service
  • Medicines for Malaria Venture
  • QIMR Berghofer Medical Research Institute
  • Southern Star Research
  • Swiss BioQuant
Data source: Medicines for Malaria Venture

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations