deltatrials
Terminated PHASE1 INTERVENTIONAL 7-arm NCT05381909

A Study of BGB-24714 as Monotherapy and With Combination Therapies in Participants With Solid Tumors

A Phase 1 Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of Second Mitochondrial-derived Activator of Caspases Mimetic BGB-24714 as Monotherapy and With Combination Therapies in Patients With Solid Tumors

Sponsor: BeiGene

Updated 26 times since 2022 Last updated: Feb 19, 2026 Started: Jul 6, 2022 Primary completion: Jul 25, 2025 Completion: Jul 25, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The research was terminated voluntarily due to changes in the company's business strategy regarding the development of BGB-24714, rather than any safety issues.

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Listed as NCT05381909, this PHASE1 trial focuses on Solid Tumor, Adult and remains terminated or withdrawn. Sponsored by BeiGene, it has been updated 26 times since 2022, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Mar 2023 · 6 months · monthly snapshot~Mar 2023 – ~Aug 2023 · 5 months · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Nov 2023 · 2 months · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Feb 2024 · 2 months · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Feb 2025 · 3 months · monthly snapshot~Feb 2025 – ~Apr 2025 · 59 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Feb 2026 · 4 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

26 versions recorded
  1. Feb 2026 — Present [monthly]

    Terminated PHASE1

    Status: Active Not RecruitingTerminated

  2. Oct 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE1

  3. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting PHASE1

  4. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE1

  5. Jul 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE1

Show 21 earlier versions
  1. Jun 2025 — Jul 2025 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  2. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE1

  3. Apr 2025 — May 2025 [monthly]

    Recruiting PHASE1

  4. Feb 2025 — Apr 2025 [monthly]

    Recruiting PHASE1

  5. Nov 2024 — Feb 2025 [monthly]

    Recruiting PHASE1

  6. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE1

  7. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE1

  8. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  9. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1

  10. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  11. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE1

  12. Apr 2024 — May 2024 [monthly]

    Recruiting PHASE1

  13. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE1

  14. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE1

  15. Dec 2023 — Feb 2024 [monthly]

    Recruiting PHASE1

  16. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE1

  17. Sep 2023 — Nov 2023 [monthly]

    Recruiting PHASE1

  18. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE1

  19. Mar 2023 — Aug 2023 [monthly]

    Recruiting PHASE1

  20. Sep 2022 — Mar 2023 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  21. Jun 2022 — Sep 2022 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • BeiGene
Data source: BeOne Medicines

For direct contact, visit the study record on ClinicalTrials.gov .