deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT05408091

Study to Evaluate Safety and Activity of TRL345 in Healthy Volunteers

A Phase 1, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of TRL345 in Healthy Volunteers

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Updated 8 times since 2022 Last updated: Apr 7, 2025 Started: Sep 14, 2023 Primary completion: Dec 23, 2024 Completion: Dec 23, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Healthy Volunteers and is currently completed. National Institute of Allergy and Infectious Diseases (NIAID) leads this study, which shows 8 recorded versions since 2023 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jul 2022 – ~Apr 2023 · 9 months · monthly snapshotNot Yet Recruiting~Apr 2023 – ~May 2023 · 30 days · monthly snapshotNot Yet Recruiting~May 2023 – ~Oct 2023 · 5 months · monthly snapshotNot Yet Recruiting~Oct 2023 – ~Jul 2024 · 9 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshotRecruiting~Dec 2024 – ~May 2025 · 5 months · monthly snapshotActive Not Recruiting~May 2025 – present · 14 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. May 2025 — Present [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  2. Dec 2024 — May 2025 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  3. Sep 2024 — Dec 2024 [monthly]

    Recruiting PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  5. Oct 2023 — Jul 2024 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

Show 3 earlier versions
  1. May 2023 — Oct 2023 [monthly]

    Not Yet Recruiting PHASE1

  2. Apr 2023 — May 2023 [monthly]

    Not Yet Recruiting PHASE1

  3. Jul 2022 — Apr 2023 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • Trellis Bioscience LLC
Data source: Trellis Bioscience LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations