Recruiting PHASE2 INTERVENTIONAL 2-arm NCT06621251

Study to Evaluate the Efficacy and Safety of TRL1068 for the Treatment of Prosthetic Joint Infection

Phase 2 Study to Evaluate the Efficacy and Safety of TRL1068 for the Treatment of Chronic Prosthetic Joint Infection of the Knee or Hip Without Exchange Arthroplasty

Sponsor: Trellis Bioscience LLC

Conditions Prosthetic Joint Infections of Hip Prosthetic Joint Infections of Knee

Interventions DAIR TRL1068 (calpurbatug), a human monoclonal antibody

Updated 9 times since 2024 Last updated: Oct 9, 2025 Started: Apr 8, 2025 Primary completion: Nov 30, 2026 Completion: Nov 30, 2026

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT06621251, this PHASE2 trial focuses on Prosthetic Joint Infections of Hip and Prosthetic Joint Infections of Knee and remains actively recruiting participants. Sponsored by Trellis Bioscience LLC, it has been updated 9 times since 2025, reflecting limited change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

Change History

9 versions recorded

Nov 2025 — Present [monthly]

Recruiting PHASE2
Sep 2025 — Nov 2025 [monthly]

Recruiting PHASE2
Aug 2025 — Sep 2025 [monthly]

Recruiting PHASE2
Jun 2025 — Aug 2025 [monthly]

Recruiting PHASE2
May 2025 — Jun 2025 [monthly]

Recruiting PHASE2

▶ Show 4 earlier versions

Apr 2025 — May 2025 [monthly]

Recruiting PHASE2

Status: Not Yet Recruiting → Recruiting
Mar 2025 — Apr 2025 [monthly]

Not Yet Recruiting PHASE2
Dec 2024 — Mar 2025 [monthly]

Not Yet Recruiting PHASE2
Oct 2024 — Dec 2024 [monthly]

Not Yet Recruiting PHASE2

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Trellis Bioscience LLC

Data source: Trellis Bioscience LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Baltimore, United States , Boston, United States , Brownsville, United States , Galveston, United States , Gilbert, United States , Houston, United States , Jacksonville, United States , Little Rock, United States , Los Angeles, United States , New York, United States and 6 more locations