deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT05543707

PBI-0451 (Pomotrelvir) Phase 2 Study in Nonhospitalized Symptomatic Adults With COVID-19

A Phase 2 Double-blind, Randomized Study to Evaluate the Antiviral Activity, Safety, and Efficacy of Orally Administered PBI-0451(Pomotrelvir) Compared With Placebo in Nonhospitalized Symptomatic Adults With COVID-19

Sponsor: Pardes Biosciences, Inc.

Conditions COVID-19
Updated 8 times since 2022 Last updated: Nov 15, 2024 Started: Sep 21, 2022 Primary completion: Jan 27, 2023 Completion: Apr 14, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Interim analysis concluded primary endpoint was not met

A PHASE2 clinical study on COVID-19, this trial is terminated or withdrawn. The trial is conducted by Pardes Biosciences, Inc. and has accumulated 8 data snapshots since 2022. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshotRecruiting~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshotRecruiting~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotRecruiting~Jan 2023 – ~Apr 2023 · 3 months · monthly snapshotRecruiting~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshotActive Not Recruiting~Jan 2025 – present · 18 months · monthly snapshotTerminated

Change History

8 versions recorded
  1. Jan 2025 — Present [monthly]

    Terminated PHASE2

    Status: Active Not RecruitingTerminated

  2. Sep 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Apr 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  5. Jan 2023 — Apr 2023 [monthly]

    Recruiting PHASE2

Show 3 earlier versions
  1. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE2

  2. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE2

  3. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Pardes Biosciences, Inc.
Data source: Pardes Biosciences, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .