deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 3-arm NCT05589597

EO4010 in Previously Treated Metastatic Colorectal Carcinoma (AUDREY)

A Global Multicenter Phase 1/2 Trial of EO4010, a Novel Microbial Derived Peptide Therapeutic Vaccine, in Combination With Nivolumab and/or Bevacizumab, for Treatment of Patients With Previously Treated Metastatic Colorectal Carcinoma

Sponsor: Enterome

Interventions EO4010
Updated 8 times since 2022 Last updated: Aug 18, 2025 Started: Jun 1, 2023 Primary completion: May 30, 2025 Completion: May 30, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Sponsor decision to stop recruitment in context of overall EO4010 development goals. Stop of recruitment was not related to any safety concern, with the safety profile of EO4010 being benign

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This PHASE1/PHASE2 trial investigates Colorectal Cancer Metastatic and is currently terminated or withdrawn. Enterome leads this study, which shows 8 recorded versions since 2023 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Nov 2022 – ~Mar 2023 · 4 months · monthly snapshotNot Yet Recruiting~Mar 2023 – ~Aug 2023 · 5 months · monthly snapshotNot Yet Recruiting~Aug 2023 – ~Nov 2023 · 3 months · monthly snapshot~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Sep 2025 · 10 months · monthly snapshotActive Not Recruiting~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

8 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE1/PHASE2

    Status: Active Not RecruitingTerminated

  2. Nov 2024 — Sep 2025 [monthly]

    Active Not Recruiting PHASE1/PHASE2

    Status: RecruitingActive Not Recruiting

  3. Sep 2024 — Nov 2024 [monthly]

    Recruiting PHASE1/PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  5. Nov 2023 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

Show 3 earlier versions
  1. Aug 2023 — Nov 2023 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  2. Mar 2023 — Aug 2023 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  3. Nov 2022 — Mar 2023 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Enterome
Data source: Enterome

For direct contact, visit the study record on ClinicalTrials.gov .