deltatrials
Recruiting PHASE2 INTERVENTIONAL 1-arm NCT05613413

A Pilot Phase II Study of Maintenance Cabozantinib Plus Pembrolizumab for Patients With Metastatic Squamous Non-Small Cell Lung Cancer (sqNSCLC) (LUNG-IST-127)

LUNG-IST-127: A Pilot Phase II Study of Maintenance Cabozantinib Plus Pembrolizumab (CP) for Patients With Metastatic sqNSCLC With Disease Control Following Induction Therapy

Sponsor: University of Illinois at Chicago

Updated 10 times since 2022 Last updated: Jan 6, 2026 Started: Dec 28, 2022 Primary completion: Sep 30, 2028 Completion: Sep 30, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05613413, this PHASE2 trial focuses on Metastatic Squamous Non-Small Cell Lung Carcinoma and remains actively recruiting participants. Sponsored by University of Illinois at Chicago, it has been updated 10 times since 2022, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotNot Yet Recruiting~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshotRecruiting~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshotRecruiting~Apr 2023 – ~Oct 2023 · 6 months · monthly snapshotRecruiting~Oct 2023 – ~Jan 2024 · 3 months · monthly snapshotRecruiting~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshotRecruiting~Mar 2025 – ~Feb 2026 · 11 months · monthly snapshotRecruiting~Feb 2026 – present · 5 months · monthly snapshotRecruiting

Change History

10 versions recorded
  1. Feb 2026 — Present [monthly]

    Recruiting PHASE2

  2. Mar 2025 — Feb 2026 [monthly]

    Recruiting PHASE2

  3. Sep 2024 — Mar 2025 [monthly]

    Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  5. Jan 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

Show 5 earlier versions
  1. Oct 2023 — Jan 2024 [monthly]

    Recruiting PHASE2

  2. Apr 2023 — Oct 2023 [monthly]

    Recruiting PHASE2

  3. Feb 2023 — Apr 2023 [monthly]

    Recruiting PHASE2

  4. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  5. Dec 2022 — Jan 2023 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University of Illinois at Chicago
Data source: University of Illinois at Chicago

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations