deltatrials
Completed PHASE3 INTERVENTIONAL 1-arm NCT05661734

A Single-arm Study to Evaluate Safety and Effectiveness of VX-548 for Acute Pain

A Phase 3, Single-arm Study Evaluating the Safety and Effectiveness of VX-548 for Acute Pain

Sponsor: Vertex Pharmaceuticals Incorporated

Conditions Pain
Interventions Suzetrigine
Updated 17 times since 2023 Last updated: Jun 13, 2025 Started: Jan 9, 2023 Primary completion: Dec 12, 2023 Completion: Dec 12, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05661734, this PHASE3 trial focuses on Pain and remains completed. Sponsored by Vertex Pharmaceuticals Incorporated, it has been updated 17 times since 2023, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Aug 2023 · 3 months · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Apr 2024 · 2 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshot~Jan 2025 – ~Aug 2025 · 7 months · monthly snapshot~Aug 2025 – present · 13 months · monthly snapshot

Change History

17 versions recorded
  1. Aug 2025 — Present [monthly]

    Completed PHASE3

  2. Jan 2025 — Aug 2025 [monthly]

    Completed PHASE3

  3. Sep 2024 — Jan 2025 [monthly]

    Completed PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  5. Apr 2024 — Jul 2024 [monthly]

    Completed PHASE3

Show 12 earlier versions
  1. Feb 2024 — Apr 2024 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  2. Jan 2024 — Feb 2024 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  3. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE3

  4. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE3

  5. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE3

  6. Sep 2023 — Oct 2023 [monthly]

    Recruiting PHASE3

  7. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE3

  8. May 2023 — Aug 2023 [monthly]

    Recruiting PHASE3

  9. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE3

  10. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE3

  11. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  12. Jan 2023 — Feb 2023 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Vertex Pharmaceuticals Incorporated
Data source: Vertex Pharmaceuticals Incorporated

For direct contact, visit the study record on ClinicalTrials.gov .