deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT05705427

The COMBAT HBV Feasibility Trial (COMBAT-HBV)

Simplifying Hepatitis B Care in Pregnancy by Combining Birth-dose Vaccine and Tenofovir: The COMBAT HBV Feasibility Trial

Sponsor: Abbott

Updated 9 times since 2023 Last updated: Feb 18, 2026 Started: Aug 17, 2023 Primary completion: Nov 25, 2025 Completion: Nov 25, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Hepatitis B and Vertical Transmission of Infectious Disease and is currently completed. Abbott leads this study, which shows 9 recorded versions since 2023 — indicating limited longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshotNot Yet Recruiting~Mar 2023 – ~May 2023 · 2 months · monthly snapshotNot Yet Recruiting~May 2023 – ~Nov 2023 · 6 months · monthly snapshotNot Yet Recruiting~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshotRecruiting~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshotActive Not Recruiting~Sep 2025 – ~Feb 2026 · 5 months · monthly snapshotActive Not Recruiting~Feb 2026 – present · 7 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Feb 2026 — Present [monthly]

    Completed PHASE4

    Status: Active Not RecruitingCompleted

  2. Sep 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE4

  3. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE4

    Status: RecruitingActive Not Recruiting

  4. Sep 2024 — Aug 2025 [monthly]

    Recruiting PHASE4

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE4

Show 4 earlier versions
  1. Nov 2023 — Jul 2024 [monthly]

    Recruiting PHASE4

    Status: Not Yet RecruitingRecruiting

  2. May 2023 — Nov 2023 [monthly]

    Not Yet Recruiting PHASE4

  3. Mar 2023 — May 2023 [monthly]

    Not Yet Recruiting PHASE4

  4. Feb 2023 — Mar 2023 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Abbott
  • Albert Einstein College of Medicine
  • Doris Duke Charitable Foundation
  • University of North Carolina, Chapel Hill
  • Université Protestant au Congo
Data source: University of North Carolina, Chapel Hill

For direct contact, visit the study record on ClinicalTrials.gov .