deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT05780437

AZD7442 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)

A Multicenter, Adaptive, Randomized, Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for Hospitalized Patients With COVID-19 (Trial H4: AZD7442)

Sponsor: Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

Conditions COVID-19
Updated 8 times since 2023 Last updated: Jan 10, 2025 Started: Feb 10, 2021 Primary completion: Jan 28, 2022 Completion: Jun 9, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on COVID-19, this trial is completed. The trial is conducted by Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections and has accumulated 8 data snapshots since 2021. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Apr 2023 – ~Jun 2023 · 2 months · monthly snapshot~Jun 2023 – ~Jun 2024 · 12 months · monthly snapshotActive Not Recruiting~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshotCompleted~Mar 2025 – ~Sep 2025 · 6 months · monthly snapshotCompleted~Sep 2025 – present · 9 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Mar 2025 — Sep 2025 [monthly]

    Completed PHASE3

  3. Sep 2024 — Mar 2025 [monthly]

    Completed PHASE3

  4. Aug 2024 — Sep 2024 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  5. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE3

Show 3 earlier versions
  1. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  2. Jun 2023 — Jun 2024 [monthly]

    Active Not Recruiting PHASE3

  3. Apr 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Feb 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
  • AstraZeneca
  • Cardiothoracic Surgical Trials Network
  • International Network for Strategic Initiatives in Global HIV Trials (INSIGHT)
  • Kirby Institute
  • Medical Research Council
  • National Heart, Lung, and Blood Institute (NHLBI)
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • Prevention and Early Treatment of Acute Lung Injury
  • US Department of Veterans Affairs
  • University of Copenhagen
  • University of Minnesota
  • Washington D.C. Veterans Affairs Medical Center
Data source: National Institute of Allergy and Infectious Diseases (NIAID)

For direct contact, visit the study record on ClinicalTrials.gov .