deltatrials
Active Not Recruiting PHASE1 INTERVENTIONAL 2-arm NCT05815160

Debio 0123 in Combination With Carboplatin and Etoposide in Adult Participants With Small Cell Lung Cancer That Recurred or Progressed After Previous Standard Platinum-Based Therapy

A Phase 1 Dose-Escalation and Expansion Study to Assess Safety and Preliminary Antitumor Activity of Debio 0123 in Combination With Carboplatin and Etoposide in Adult Participants With Small Cell Lung Cancer That Recurred or Progressed After Previous Standard Platinum-Based Therapy

Sponsor: Debiopharm International SA

Conditions Small Cell Lung Cancer Recurrent
Interventions Carboplatin Debio 0123 Etoposide
Updated 29 times since 2023 Last updated: Feb 26, 2026 Started: May 2, 2023 Primary completion: Mar 31, 2026 Completion: Mar 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05815160, this PHASE1 trial focuses on Small Cell Lung Cancer Recurrent and remains ongoing. Sponsored by Debiopharm International SA, it has been updated 29 times since 2023, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Jun 2024 · 4 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Jan 2025 · 31 days · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~May 2025 · 2 months · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

29 versions recorded

  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE1

  2. Jan 2026 — Feb 2026 [monthly]

    Active Not Recruiting PHASE1

  3. Dec 2025 — Jan 2026 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  4. Nov 2025 — Dec 2025 [monthly]

    Recruiting PHASE1

  5. Sep 2025 — Nov 2025 [monthly]

    Recruiting PHASE1

▶ Show 24 earlier versions

  1. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE1

  2. Jul 2025 — Aug 2025 [monthly]

    Recruiting PHASE1

  3. Jun 2025 — Jul 2025 [monthly]

    Recruiting PHASE1

  4. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE1

  5. Mar 2025 — May 2025 [monthly]

    Recruiting PHASE1

  6. Feb 2025 — Mar 2025 [monthly]

    Recruiting PHASE1

  7. Jan 2025 — Feb 2025 [monthly]

    Recruiting PHASE1

  8. Dec 2024 — Jan 2025 [monthly]

    Recruiting PHASE1

  9. Nov 2024 — Dec 2024 [monthly]

    Recruiting PHASE1

  10. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE1

  11. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE1

  12. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  13. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1

  14. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  15. Feb 2024 — Jun 2024 [monthly]

    Recruiting PHASE1

  16. Jan 2024 — Feb 2024 [monthly]

    Recruiting PHASE1

  17. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE1

  18. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE1

  19. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE1

  20. Sep 2023 — Oct 2023 [monthly]

    Recruiting PHASE1

  21. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE1

  22. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE1

  23. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  24. May 2023 — Jun 2023 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Debiopharm International SA
Data source: Debiopharm International SA

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations