deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 3-arm NCT05819359

Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD (ACTIVATE)

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in Subjects With Parkinson's Disease With a Pathogenic Variant in the Glucocerebrosidase (GBA1) Gene

Sponsor: Bial R&D Investments, S.A.

Updated 10 times since 2023 Last updated: Dec 4, 2025 Started: Mar 31, 2023 Primary completion: Mar 31, 2026 Completion: Jul 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Parkinson's Disease, this trial is ongoing. The trial is conducted by Bial R&D Investments, S.A. and has accumulated 10 data snapshots since 2023. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~May 2023 – ~Aug 2023 · 3 months · monthly snapshotRecruiting~Aug 2023 – ~Nov 2023 · 3 months · monthly snapshotRecruiting~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Apr 2024 · 4 months · monthly snapshotRecruiting~Apr 2024 – ~Jun 2024 · 2 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotActive Not Recruiting~Sep 2025 – ~Jan 2026 · 4 months · monthly snapshotActive Not Recruiting~Jan 2026 – present · 4 months · monthly snapshotActive Not Recruiting

Change History

10 versions recorded
  1. Jan 2026 — Present [monthly]

    Active Not Recruiting PHASE2

  2. Sep 2025 — Jan 2026 [monthly]

    Active Not Recruiting PHASE2

  3. Sep 2024 — Sep 2025 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  5. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

Show 5 earlier versions
  1. Apr 2024 — Jun 2024 [monthly]

    Recruiting PHASE2

  2. Dec 2023 — Apr 2024 [monthly]

    Recruiting PHASE2

  3. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE2

  4. Aug 2023 — Nov 2023 [monthly]

    Recruiting PHASE2

  5. May 2023 — Aug 2023 [monthly]

    Recruiting PHASE2

    First recorded

Mar 2023

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bial R&D Investments, S.A.
Data source: Bial R&D Investments, S.A.

For direct contact, visit the study record on ClinicalTrials.gov .