deltatrials
Recruiting PHASE3 INTERVENTIONAL 2-arm NCT05819853

Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome (RESTORE)

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Updated 9 times since 2023 Last updated: Aug 21, 2025 Started: Nov 3, 2023 Primary completion: Feb 1, 2028 Completion: Jun 30, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Obese and PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries and is currently actively recruiting participants. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) leads this study, which shows 9 recorded versions since 2023 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Sep 2023 · 3 months · monthly snapshot~Sep 2023 – ~Dec 2023 · 3 months · monthly snapshot~Dec 2023 – ~May 2024 · 5 months · monthly snapshotRecruiting~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotRecruiting~Sep 2025 – present · 10 months · monthly snapshotRecruiting

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Recruiting PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Recruiting PHASE3

  3. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  4. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE3

  5. May 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

Show 4 earlier versions
  1. Dec 2023 — May 2024 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  2. Sep 2023 — Dec 2023 [monthly]

    Not Yet Recruiting PHASE3

  3. Jun 2023 — Sep 2023 [monthly]

    Not Yet Recruiting PHASE3

  4. May 2023 — Jun 2023 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
  • University of Colorado, Denver
Data source: University of Colorado, Denver

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations