deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 2-arm NCT05941741

IC Plus Low-dose Radiation Plus Cadonilimab in LANPC

Induction Chemotherapy Combined With Low-dose Radiation Plus Cadonilimab in Loco-regionally Advanced Nasopharyngeal Carcinoma: a Multi-center, Open-label, Randomized Controlled Phase III Clinical Trial

Sponsor: Sun Yat-Sen University Cancer Center

Conditions Chemotherapy Immune Checkpoint Inhibitor Nasopharyngeal Carcinoma Radiotherapy
Interventions Chemotherapy Immune checkpoint inhibitor Intensity Modulated Radiation Therapy Low-dose radiotherapy
Updated 8 times since 2023 Last updated: May 13, 2025 Started: Jan 10, 2024 Primary completion: Dec 31, 2026 Completion: Dec 31, 2029
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Chemotherapy and Immune Checkpoint Inhibitor, this trial is ongoing. The trial is conducted by Sun Yat-Sen University Cancer Center and has accumulated 8 data snapshots since 2024. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Aug 2023 – ~Dec 2023 · 4 months · monthly snapshotNot Yet Recruiting~Dec 2023 – ~Feb 2024 · 2 months · monthly snapshot~Feb 2024 – ~Apr 2024 · 2 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshotRecruiting~Jun 2025 – ~Mar 2026 · 9 months · monthly snapshotActive Not Recruiting~Mar 2026 – present · 6 months · monthly snapshotActive Not Recruiting

Change History

8 versions recorded

  1. Mar 2026 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Jun 2025 — Mar 2026 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  3. Sep 2024 — Jun 2025 [monthly]

    Recruiting PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  5. Apr 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

▶ Show 3 earlier versions

  1. Feb 2024 — Apr 2024 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  2. Dec 2023 — Feb 2024 [monthly]

    Not Yet Recruiting PHASE3

  3. Aug 2023 — Dec 2023 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Sun Yat-Sen University Cancer Center
Data source: Sun Yat-sen University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations