deltatrials
Active Not Recruiting PHASE4 INTERVENTIONAL 5-arm NCT05942222

A Real-world, Head-to-head Comparison of Dupilumab Versus Mepolizumab in Danish Patients With Chronic Rhinosinusitis With Nasal Polyps (TORNADO)

Treatment of Rhinosinusitis With Nasal Polyposis With Dupilumab and Mepolizumab: A Randomized, Multi-centre, Head-to-head Comparison in Real-world Danish Patients

Sponsor: Rigshospitalet, Denmark

Updated 4 times since 2023 Last updated: Jun 25, 2025 Started: Apr 27, 2023 Primary completion: Apr 1, 2026 Completion: May 1, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05942222, this PHASE4 trial focuses on Asthma; Eosinophilic and Chronic Rhinosinusitis With Nasal Polyps and remains ongoing. Sponsored by Rigshospitalet, Denmark, it has been updated 4 times since 2023, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshotRecruiting~Aug 2025 – present · 11 months · monthly snapshotActive Not Recruiting

Change History

4 versions recorded
  1. Aug 2025 — Present [monthly]

    Active Not Recruiting PHASE4

    Status: RecruitingActive Not Recruiting

  2. Sep 2024 — Aug 2025 [monthly]

    Recruiting PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE4

  4. Aug 2023 — Jul 2024 [monthly]

    Recruiting PHASE4

    First recorded

Apr 2023

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Rigshospitalet, Denmark
Data source: Rigshospitalet, Denmark

For direct contact, visit the study record on ClinicalTrials.gov .