Recruiting PHASE3 INTERVENTIONAL 2-arm NCT05974462

MYTHS-MR Trial (MYocarditis THerapy With Steroids in Patients With Mildly Reduced Ejection Fraction) (MYTHS-MR)

Single-blind, Investigator-initiated, Randomized, Controlled Trial to Assess the Safety and Efficacy of Intravenous Corticosteroid Therapy to Treat Patients With Acute Myocarditis With Mildly Reduced Left Ventricular Ejection Fraction

Sponsor: Niguarda Hospital

Conditions Acute Myocarditis

Interventions IV saline solution 0.9% Methylprednisolone 125 MG

Updated 8 times since 2023 Last updated: Apr 14, 2025 Started: May 24, 2024 Primary completion: Oct 1, 2026 Completion: Oct 1, 2028

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Acute Myocarditis, this trial is actively recruiting participants. The trial is conducted by Niguarda Hospital and has accumulated 8 data snapshots since 2024. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Recruiting PHASE3
May 2025 — Sep 2025 [monthly]

Recruiting PHASE3
Sep 2024 — May 2025 [monthly]

Recruiting PHASE3
Aug 2024 — Sep 2024 [monthly]

Recruiting PHASE3
Jul 2024 — Aug 2024 [monthly]

Recruiting PHASE3

Status: Not Yet Recruiting → Recruiting

▶ Show 3 earlier versions

Dec 2023 — Jul 2024 [monthly]

Not Yet Recruiting PHASE3
Oct 2023 — Dec 2023 [monthly]

Not Yet Recruiting PHASE3
Sep 2023 — Oct 2023 [monthly]

Not Yet Recruiting PHASE3

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Niguarda Hospital
University Hospital, Antwerp

Data source: University Hospital, Antwerp

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

A Coruña, Spain , Aalst, Belgium , Antwerp, Belgium , Arezzo, Italy , Bergamo, Italy , Brescia, Italy , Edegem, Belgium , Florence, Italy , Hasselt, Belgium , Lecco, Italy and 7 more locations