deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT05987176

Comparison of Adjuvant Treatment With 177Lu-DOTATATE to Best Supportive Care in Patients After Resection of Neuroendocrine Liver Metastases (NELMAS)

An International Multicentre Randomized Unblinded Phase II Study Comparing Adjuvant Treatment With 177Lu-DOTATATE (Lutathera®) to Best Supportive Care in Patients After Resection of Neuroendocrine Liver Metastases

Sponsor: Imperial College London

Interventions Lutathera
Updated 4 times since 2023 Last updated: Jan 13, 2026 Started: Aug 2, 2024 Primary completion: Oct 21, 2025 Completion: Oct 21, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study has closed earlier than planned due to one of the funders decision to withdraw the financial support for the study.

A PHASE2 clinical study on Gastroenteropancreatic Neuroendocrine Neoplasm and Gastroenteropancreatic Neuroendocrine Tumor, this trial is terminated or withdrawn. The trial is conducted by Imperial College London and has accumulated 4 data snapshots since 2024. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshotNot Yet Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2026 · 17 months · monthly snapshotRecruiting~Feb 2026 – present · 5 months · monthly snapshotTerminated

Change History

4 versions recorded
  1. Feb 2026 — Present [monthly]

    Terminated PHASE2

    Status: RecruitingTerminated

  2. Sep 2024 — Feb 2026 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  3. Jul 2024 — Sep 2024 [monthly]

    Not Yet Recruiting PHASE2

  4. Sep 2023 — Jul 2024 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Imperial College London
  • Novartis/AAA
  • The Taylor Family 2010 Charitable Trust
Data source: Imperial College London

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations