deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT03980925

Platinum-doublet Chemotherapy and Nivolumab for the Treatment of Subjects With Neuroendocrine Neoplasms (NENs) of the Gastroenteropancreatic (GEP) Tract or of Unknown (UK) Origin.

A Phase II Study of Platinum-doublet Chemotherapy in Combination With Nivolumab as First-line Treatment in Subjects With Unresectable, Locally Advanced or Metastatic G3 Neuroendocrine Neoplasms (NENs) of the Gastroenteropancreatic (GEP) Tract or of Unknown (UK) Origin.

Sponsor: Grupo Espanol de Tumores Neuroendocrinos

Updated 14 times since 2019 Last updated: Nov 22, 2024 Started: Oct 11, 2019 Primary completion: Feb 13, 2023 Completion: Jun 9, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Gastroenteropancreatic Neuroendocrine Tumor and Neuroendocrine Neoplasm and is currently completed. Grupo Espanol de Tumores Neuroendocrinos leads this study, which shows 14 recorded versions since 2019 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jul 2019 – ~Sep 2019 · 2 months · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~May 2020 · 7 months · monthly snapshot~May 2020 – ~Jan 2021 · 8 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Sep 2021 · 6 months · monthly snapshot~Sep 2021 – ~Apr 2022 · 7 months · monthly snapshot~Apr 2022 – ~Sep 2022 · 5 months · monthly snapshot~Sep 2022 – ~Mar 2023 · 6 months · monthly snapshot~Mar 2023 – ~Jul 2024 · 16 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Sep 2025 · 7 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Feb 2025 — Sep 2025 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  3. Sep 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Mar 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

Show 9 earlier versions
  1. Sep 2022 — Mar 2023 [monthly]

    Recruiting PHASE2

  2. Apr 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  3. Sep 2021 — Apr 2022 [monthly]

    Recruiting PHASE2

  4. Mar 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  5. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  6. May 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  7. Oct 2019 — May 2020 [monthly]

    Not Yet Recruiting PHASE2

  8. Sep 2019 — Oct 2019 [monthly]

    Not Yet Recruiting PHASE2

  9. Jul 2019 — Sep 2019 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Grupo Espanol de Tumores Neuroendocrinos
Data source: Grupo Espanol de Tumores Neuroendocrinos

For direct contact, visit the study record on ClinicalTrials.gov .